Yes. NAD+ patches utilize iontophoresis technology with a small integrated battery that supports transdermal delivery of NAD+ into the bloodstream. Due to this active delivery mechanism, the patches are classified as a medical device and are available only with a prescription.

The typical recommendation is to wear the NAD+ patch once per week for approximately four hours. Usage frequency may be adjusted based on factors such as age, individual NAD+ depletion levels, and personal health objectives.

For optimal adhesion, the patch should be applied to an area with little or no hair. Commonly recommended locations include the upper arm, abdomen, back, or thigh.